Basic Drug Interactions
Basic drug interactions (updated 6/8/13) – 1.1 Session overview
Module: Basic introduction to HIV drug interactions
Duration: 30 minutes reading and exercises, 40 minute video presentations
Author: Neal Marshall, Royal Free Hospital, London
First published: 25th March 2012. Updated 6/8/13
Next review: 6th August 2014
Description: This section covers the basics of antiretroviral drug interactions with respect to antiretrovirals. It composes a series of slides, a set of reference resources, and a video presentations from the HIV in 2012 study day in March 2012, and a presntaion by Prof David Back looking at drug interactions with cobicistat/elvitegrav
Basic drug interactions – 1.2 module learning objectives
By the end of this session you will be:
- Aware of key hepatic enzymes by which many drugs are metabolised
- Aware of resources for identifying drug interactions
- Aware of complexity of switching ARVs
- Aware of some of the key drug interactions with ARVs (including cobicistat and elvitegravir)
Links
Basic drug interactions – 1.3 Educational resources
The following sites and guidelines provide some excellent learning resources and presentations on drug interactions:
Basic drug interactions – 1.4 Drug interaction websites
The following are the most useful websites to deliver information on specific drug-drug interactions
Links to these and other resources are found in the www.hivpa.org links page
Basic drug interactions – 1.5 Practice session
Go to the Liverpool drug interactions website and look for the interactions between the following drugs. If there is no information use other resources to research the interaction:
- Atazanavir and ranitidine
- Lopinavir and carbamazepine
- Efavirenz and rifampicin
- Ritonavir and triamcinolone injection
Basic drug interactions – 1.6 Video presentation
The presentations below were given at the HIVPA ‘HIV in 2012′ study day in March 2012 by Neal Marshall, and by Prof David Back (Univeristy of Liverpool) in July 2013 were he spoke about drug interactiosn with cobicistat and elvitegravir
Now use the link below to view each 40 minute presentation on basic drug interactions seen in HIV, and then cobicistat/elvitegravir interactions .
Some NHS servers may have difficulty in viewing Adobe Connect presentations. Contact your local IT services if you have problems and please let us know if you have continuing problems at www.hivpa.org@gmail.com
If you cannot hear any sound please check that your sound is not set to mute and is turned up sufficiently (typically on the bottom right of your windows tool bar). NHS computers may not have speakers attached so you may need headphones
There will be some questions to follow based on the first presentation
Basic drug interactions – 1.7 Post module quiz
Thank you for completing the HIVPA eHIVe basic drug interactions module.
Below there is a series of questions based on the learning objectives of the module and presentation. Once you have answered the questions the website will create you a module completion certificate for you to download and use as part of you CPD requirements.