HIV and the kidney – Dr. Rachael Jones Welcome to your HIV and the kidney - Dr. Rachael Jones Regarding eGFR, which of the following is true? a. Works well for individuals with poor renal function b. Works well at extremes of BMI c. Very accurate when renal function >60ml/min/1.73 M2 d. It is safe to rely on only one reading e. Is not directly linked to serum creatinine In the D:A:D study investigating the association between ARV exposure and renal impairment among HIV positive individuals with normal baseline renal function, what percentage of individuals studied developed CKD after a median follow up of 4.5 years? a. 40% b. 30% c. 20% d. 10% e. 1% In individuals with CKD, it is important to control BP to prevent cardiovascular disease and CKD progression. This may require lifestyle intervention and multiple pharmaceutical agents until the systolic blood pressure is: a. <170mmHg b. <160mmHg c. 150 d. 140mm e. 130mm When looking at acute kidney injury (AKI) in individuals living with HIV, which of the following is not true a. It is common in the first 3 months following HIV diagnosis b. Infection is a common cause c. Malignancy is a common cause d. Drugs are a common cause e. AKI has a good prognosis Which of the following drugs has the fewest reports of renal effects? a. Raltegravir b. Elvitegravir c. Dolutegravir d. Cobicistat e. Rilpivinine Time is Up!